tert-butyl (5-bromopyrimidin-2-yl)carbamate

tert-butyl (5-bromopyrimidin-2-yl)carbamate - Names and Identifiers

Name	tert-butyl (5-bromopyrimidin-2-yl)carbamate
Synonyms	5-Bromo-N-Boc-pyrimidin-2-amine N-Boc-2-AMino-5-broMopyriMidine 2-(N-BOC-Amino)-5-bromopyrimidine (5-Bromopyrimidin-2-yl)tert-butylcarbamate tert-butyl (5-broMo-2-pyriMidinyl)carbaMate tert-Butyl (5-bromopyrimidin-2-yl)carbamate tert-butyl (5-bromopyrimidin-2-yl)carbamate (5-Bromo-pyrimidin-2-yl)-carbamic acid tert-butyl ester
CAS	883231-23-0
InChI	InChI=1/C9H12BrN3O2/c1-9(2,3)15-8(14)13-7-11-4-6(10)5-12-7/h4-5H,1-3H3,(H,11,12,13,14)

tert-butyl (5-bromopyrimidin-2-yl)carbamate - Physico-chemical Properties

Molecular Formula	C9H12BrN3O2
Molar Mass	274.11
Density	1.513±0.06 g/cm3(Predicted)
pKa	10.38±0.70(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
Refractive Index	1.576

tert-butyl (5-bromopyrimidin-2-yl)carbamate - Introduction

tert-butyl (5-bromopyrimidin-2-yl)carbamate is an organic compound containing a Boc protecting group (tert-butoxycarbonyl) and a bromopyrimidine ring in its chemical structure.

Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 140-144 ℃
-Solubility: Soluble in organic solvents such as methanol, ethanol and dichloromethane

Use:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
-can be used to synthesize drugs, pesticides, photosensitizers and other organic compounds.

Preparation Method:
The preparation of tert-butyl (5-bromopyrimidin-2-yl)carbamate usually uses the following steps:
1. 5-bromopyrimidine was reacted with tri-tert-butoxycarbonyl amine to obtain tert-butyl (5-bromopyrimidin-2-yl)carbamate.

Safety Information:
- tert-butyl (5-bromopyrimidin-2-yl)carbamate has limited toxicity data, but it is usually necessary to take appropriate precautions when working in the laboratory, such as wearing gloves and safety glasses.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-This compound is potentially irritating and allergenic and should be handled with caution and stored properly. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:18:00